66 – Cierpicki, T. & Otlewski, J. (2000) Determination of a High Precision Structure of a Novel Protein Linum usitatissimum Trypsin Inhibitor (LUTI) Using Computer Aided Assignment of NOESY Crosspeaks. J. Mol. Biol. 302, 1179-1192. [PubMed]

65 – Jakimowicz, P., Ostropolska, L., Pruchnik, F.P. (2000) Interaction of [Rh2(O2CCH3)4(H2O)2] and [Rh2(O2CCH(OH)Ph)2(phen)2(H2O)2](O2CCH(OH)Ph)2  with sulfhydryl compounds and ceruloplasmin. Met Based Drugs. 7(4), 201-209 [PubMed]

64 – Galdecka, E., Galdecki, Z., Pruchnik, F.P., Jakimowicz, P. (2000) Structure and properties of diacetato-dichlorobis(2,2′-bipyridine)dirhodium(II)-trihydrate”  Transition Met. Chem. 25, 315-319. [link]

63 – Grzesiak, A., Helland, R., Smalås, A.O., Krowarsch, D., Dadlez, M. & Otlewski, J. (2000) Substitutions at the P1′ Position in BPTI is a Major Determinant of the Association Energy with Serine Proteinases. J. Mol. Biol.301, 207-218.[PubMed]

62 – Grzesiak, A., Krokoszynska, I., Krowarsch, D., Dadlez, M. & Otlewski, J. (2000) Inhibition of Six Serine Proteinases of the Human Coagulation System by Mutants of Bovine Pancreatic Trypsin Inhibitor. J. Biol. Chem. 275, 33346-33352.[PubMed]

61 – Cierpicki, T., Bania, J. & Otlewski, J. (2000) NMR Solution Structure of Apis mellifera Chymotrypsin/Cathepsin G Inhibitor-1 (AMCI-1): Structural Similarity with Ascaris Protease Inhibitors. Protein Science 9, 976-84. [PubMed]

60 – Grzesiak, A., Buczek, O., Petry, I., Szewczuk, Z. & Otlewski, J. (2000) Inhibition of Serine Proteinases from Human Blood Clotting System by Squash Inhibitor Mutants. Biochim. Biophys. Acta1478, 318-324. [PubMed]

59 – Favre, I., Moss, G.W.J., Goldenberg, D.P., Otlewski, J. & Moczydlowski, E. (2000) Structure-Activity Relationships for the Interaction of Bovine Pancreatic Trypsin Inhibitor with an Intracellular Site on a Large Conductance Ca2+-activated K+ Channel. Biochemistry 39, 2001-2012. [PubMed]

58 – Czapinska, H., Otlewski, J., Krzywda, S., Sheldrick, G.M. & Jaskólski, M. (2000) High Resolution Structure of Bovine Pancreatic Trypsin Inhibitor with Altered Binding Loop Sequence. J. Mol. Biol. 295, 1237-1249. [PubMed]

57 – Bien, M., Pruchnik, F.P., Seniuk, A., Lachowicz, T.M., Jakimowicz, P. (1999) Studies of antibacterial activity of binuclear rhodium(II) complexes with heterocyclic nitrogen ligands. J. Inorg. Bioch. 73, 49-55. [PubMed]

56 – Otlewski, J., Krowarsch, D. & Apostoluk, W. (1999) Protein Inhibitors of Serine Proteinases. Acta Biochim. Polon. 46, 531-565. [PubMed]

55 – Krowarsch, D., Dadlez, M., Buczek, O., Krokoszynska, I., Smalås, A.O. & Otlewski, J. (1999) Interscaffolding Additivity: Binding of P1 Variants of Bovine Pancreatic Trypsin Inhibitor to Four Serine Proteases. J. Mol. Biol. 289, 175-186. [PubMed]

54 – Helland, R., Otlewski, J., Sundheim, O., Dadlez, M. & Smalås, A.O. (1999) The Crystal Structures of the Complexes Between Bovine β-Trypsin and Ten P1 Variants of BPTI. J. Mol. Biol. 287, 923-942. [PubMed]

53 – Czapinska, H. & Otlewski, J. (1999) Structural and Energetic Determinants of the S1 Site Specificity in Serine Proteases. Eur. J. Biochem. 260, 571-595. [PubMed]

52 – Kiczak, L., Koscielska, K., Otlewski, J., Czerwinski, M. & Dadlez, M. (1999) Phage Display Selection of P1 Mutants of BPTI Directed against Five Different Serine Proteinases. Biol. Chem. 380, 101-105. [PubMed]

51 – Helland, R., Berglund, G.I., Andersen, O.A., Smalås, A.O., Willassen, N.P., Apostoluk, W. & Otlewski, J. (1999) High Resolution Crystal Structures of Three New Trypsin-Squash Inhibitor Complexes. Detailed Comparison with Other Trypsins and Their Complexes. Acta Cryst. D55, 139-148. [PubMed]

50 – Koscielska, K., Kiczak, L., Kasztura, M., Wesolowska, O. & Otlewski, J. (1998) Phage Display of Proteins. Acta Biochim. Polon. 45, 705-720. [PubMed]

49 – Apostoluk, W. & Otlewski, J. (1998) Variability of the Canonical Loop Conformations in Serine Proteinases Inhibitors and Other Proteins. Proteins: Struct. Funct. Genet. 32, 459-474. [PubMed]

48 – Polanowska, J., Krokoszynska, I., Czapinska, H., Watorek, W., Dadlez, M. & Otlewski, J. (1998) Specificity of Human Cathepsin G. Biochim. Biophys. Acta 1386, 189-198. [PubMed]

47 – Krokoszynska, I., Dadlez, M. & Otlewski, J. (1998) Structure of Single-disulfide Variants of Bovine Pancreatic Trypsin Inhibitor (BPTI) as Probed by Their Binding to Bovine β-Trypsin. J. Mol. Biol. 275, 503-513. [PubMed]

46 – Otlewski, J., Apostoluk, W., Buczek, O., Cholawska, L., Grzesiak, A., Koscielska, K., Krokoszynska, I., Krowarsch, D., Stachowiak, D. & Dadlez, M. (1997) Structural and Energetic Aspects of Protein Inhibitor-Serine Proteinase Recognition. In: Trends in Protein Research. (Legocki, A.B & Soda, K. eds.) Scientific Publishers, Poznan, pp. 49-58. [PubMed]

45 – Otlewski, J. & Apostoluk, W. (1997) Structural and Energetic Aspects of Protein-Protein Recognition. Acta Biochim. Polon. 44, 367-388. [PubMed]

44 – Otlewski, J. & Krowarsch, D. (1996) Squash Inhibitor Family of Serine Proteinases. Acta Biochim. Polon. 43, 431-444. [PubMed]

43 – Otlewski, J., Sywula, A., Kolasinski, M. & Krowarsch, D. (1996) Unfolding Kinetics of Bovine Trypsinogen. Eur. J. Biochem. 242, 601-607. [PubMed]

42 – Krokoszynska, I. & Otlewski, J. (1996) Thermodynamic Stability Effects of Single Peptide Bonds Hydrolysis in Protein Inhibitors of Serine Proteinases. J. Mol. Biol. 256, 793-802. [PubMed]

41 – Bolewska, K., Krowarsch, D., Otlewski, J., Jaroszewski, £. & Bierzynski, A. (1995) Synthesis, Cloning and Expression in E. coli of Met8->Leu Variant of Cucurbita maxima Trypsin Inhibitor I, a Representative of Squash Inhibitor Family. FEBS Lett. 377, 172-174. [PubMed]

40 – Bulaj, G. & Otlewski, J. (1995) Ligand-Induced Changes in the Conformational Stability of Bovine Trypsinogen and Their Implications for the Protein Function. J. Mol. Biol. 247, 701-716. [PubMed]

39 – Bulaj, G. & Otlewski, J. (1994) Denaturation of Free and Complexed Bovine Trypsinogen with the Calcium Ion, Dipeptide Ile-Val and Basic Pancreatic Trypsin Inhibitor (Kunitz). Eur. J. Biochem. 223, 939-946. [PubMed]

38 – Wells, J.A., Fairbrother, W.J., Otlewski, J., Laskowski, M.Jr. & Burnier, J. (1994) A Reinvestigation of a Synthetic Peptide (TrPepz) Designed to Mimic Trypsin. Proc. Natl. Acad. Sci. USA 91, 4110-4114. [PubMed]

37 – Otlewski, J., Zbyryt, T., Dryjanski, M., Bulaj, G. and Wilusz, T. (1994) Single Peptide Bond Hydrolysis/Resynthesis in Squash Inhibitors of Serine Proteinases. II. Limited Proteolysis of Cucurbita maxima Trypsin Inhibitor I (CMTI I) by Pepsin. Biochemistry 33, 208-213. [PubMed]

36 – Otlewski, J. & Zbyryt, T. (1994) Single Peptide Bond Hydrolysis/Resynthesis in Squash Inhibitors of Serine Proteinases. I. Kinetics and Thermodynamics of the Interaction betwwen Squash Inhibitors and Bovine β-Trypsin. Biochemistry 33, 200-207. [PubMed]

35 – Otlewski, J. (1993) The Squash Inhibitors of Serine Proteinases. In: Innovations on Proteases and their Inhibitors (F.X. Aviles, ed.) Walter de Gruyter, Berlin, pp. 369-390. [PubMed]

34 – Rozycki, J., Kupryszewski, G., Rolka, K., Ragnarsson, U., Zbyryt, T., Krokoszynska, I., Otlewski, J. (1993) Glycine-rich Analogues of Cucurbita maxima Trypsin Inhibitor (CMTI-III) Substituted by Valine in Position 27 Display Relatively Low Antitrypsin Activity. Biol. Chem. Hoppe-Seyler 374, 851-854. [PubMed]

33 – Habazettl, J., Schleicher, M., Otlewski, J. & Holak, T. A. (1992). Homonuclear Three-Dimensional NOE-NOE Nuclear Magnetic Resonance Spectra for Structure Determination Proteins in Solution. J. Mol. Biol. 228, 156-169.[PubMed]

32 – Rolka, K., Kupryszewski, G., Rozycki, J., Ragnarsson, U., Zbyryt, T., Otlewski, J. & Wliusz, T. (1992). Trypsin Inhibitor (CMTI I III) from Squash seeds: New Synthetic Analogues with Simplified Structure. In: Peptides 1992 (C.H. Schneider and A.N. Eberle, eds.) ESCOM Science Publ. 776-777. [link]

31 – Rolka, K., Kupryszewski, G., Rozycki, J., Ragnarsson, U., Zbyryt, T. & Otlewski, J. (1992). Fully Active Synthetic Analogue of Cucurbita maxima Trypsin Inhibitor III (CMTI III) Monosubstituted with Glycine in Position 9. Pol. J. Chem. 66, 2009-2013.

30 – Rolka, K., Kupryszewski, G., Rozycki, J., Ragnarsson, U., Zbyryt, T. & Otlewski, J. (1992). New Analogues of Cucurbita maxima Trypsin Inhibitor III (CMTI I III) with Simplified Structure. Biol. Chem. Hoppe-Seyler 373, 1055-1060.[PubMed]

29 – Habazettl, J., Gondol, D., Wiltscheck, R., Otlewski, J., Schleicher, M. & Holak, T. A. (1992). Structure of Hisactophilin is Similar to Interleukin-lβ and Fibroblast Growth Factor. Nature 359, 855-858. [PubMed]

28 – Holak, T. A., Habazettl, J., Oschkinat, H. & Otlewski, J. (1991). Structures of Proteins in Solution Derived from Homonuclear Three-Dimensional NOE-NOE Nuclear Magnetic Resonance Spectroscopy. High Resolution Structure of Squash Trypsin Inhibitor. J. Am. Chem. Soc. 113, 3196-3198. [link]

27 – Rolka, K., Kupryszewski, G., Ragnarsson, U., Otlewski, J., Krokoszynska, I. & Wilusz, T. (1991). Chemical Synthesis of New Trypsin, Chymotrypsin and Elastase Inhibitors by Amino-Acid Substitutions in a Trypsin Inhibitor from Squash Seeds (CMTI I). Biol. Chem. Hoppe-Seyler 372, 63-68. [PubMed]

26 – Zbyryt, T. & Otlewski, J. (1991). Interaction between Squash Inhibitors and Bovine Trypsinogen. Biol. Chem. Hoppe-Seyler 372, 255-262. [PubMed]

25 – Rolka, K., Kupryszewski, G., Ragnarsson, U., Otlewski, J., Krokoszynska, I. & Wilusz, T. (1991). New Synthetic Aanlogues of Trypsin Inhibitor CMTI-III from Squash Seeds. In: Peptides 1990. Proceedings of the Twenty-First European Peptide Symposium (E. Giralt and D. Andreu, eds.) ESCOM Science Publ., pp. 768-771.

24 – Otlewski, J. (1990). Stability of Globular Proteins. The Case of Ovomucoid Third Domains. (in Polish). Acta Univ. Wratislaviensis, 1269.

23 – Stachowiak, K., Otlewski, J., Polanowski, A. & Dyckes, D. F. (1990). Monitoring Protein Cleavage and Concurrent Disulfide Bond Assignment Using Thermospray LC/MS. Peptide Res. 3, 148-154. [PubMed]

22 – Otlewski, J. (1990). Trypsin Inhibitors from Cucurbitaceae Plants. Zeszyty Nauk. Uniw. Jagiellon.986, 69-75.

21 – Dryjanski, M., Otlewski, J. & Wilusz, T. (1990). Serine Proteinase from Cucurbita ficifolia Seeds. Acta Biochim. Polon. 37, 169-172. [PubMed]

20 – Otlewski, J., Zbyryt, T., Krokoszynska, I. & Wilusz, T. (1990). Inhibition of Serine Proteinases by Squash Inhibitors. Biol. Chem. Hoppe-Seyler 371, 589-594. [PubMed]

19 – Dryjanski, M., Otlewski, J., Polanowski, A. & Wilusz, T. (1990). Serine Proteinase from Cucurbita ficifolia Seed; Purification, Properties, Substrate Specificity and Action on Native Squash Trypsin Inhibitor (CMTI I). Biol. Chem. Hoppe-Seyler 371, 889-895. [PubMed]

18 – Otlewski, J. (1990). The Squash Inhibitor Family of Serine Proteinases. Biol. Chem. Hoppe-Seyler 371, 23-28.[PubMed]

17 – Holak, T. A., Bode, W., Huber, R., Otlewski, J. & Wilusz, T. (1989). N.M.R. Solution and X-Ray Structures of Squash Trypsin Inhibitor Exhibit the Same Conformation of the Proteinase Binding Loop. In: Proteinases and Their Inhibitors. Recent Developments. (E. Auerswald, H. Fritz and V. Turk, eds.) Weka-Druck, Linnich, pp. 95-97.

16 – Bode, W., Greyling, J., Huber, R., Otlewski, J. & Wilusz, R. (1989). The X-Ray Crystal Structure of the Complex Formed between Bovine β-Trypsin and CMTI I, a Trypsin Inhibitor from Squash Seeds. In: Proteinases and Their Inhibitors: Recent Developments (E. Auerswald, H. Fritz and V. Turk, eds.) Weka-Druck, Linnich, pp. 85-90.

15 – Holak, T., Gondol, D., Otlewski, J. & Wilusz, T. (1989). Determination of the Complete Three-Dimensional Structure of the Trypsin Inhibitor from Squash Seeds in Aqueous Solution by Nuclear Magnetic Resonance and a Combination of Distance Geometry and Simulated Annealing. J. Mol. Biol.210, 635-648. [PubMed]

14 – Holak, T., Bode, W., Huber, R., Otlewski, J. & Wilusz T. (1989). N.M.R. Solution and X-Ray Structures of Squash Inhibitor Exhibit the Same Conformation of the Proteinase Binding Loop. J. Mol. Biol. 210, 649-654. [PubMed]

13 – Rolka, K., Kupryszewski, G., Ragnarsson, U., Otlewski, J., Wilusz, T. & Polanowski, A. (1989). Synthesis of an Elastase Inhibitor by Monosubstitution of Arg5 with Val at the Reactive Site in a Trypsin Inhibitor from Squash Seeds (CMTI III). Biol. Chem. Hoppe-Seyler 370, 499-502. [PubMed]

12 – Polanowski, A., Wilimowska-Pelc, A., Kolaczkowska, M. K., Olichwier, Z., Leluk, J., Otlewski, J. & Wilusz, T. (1989). Proteolytic Enzymes and Their Naturally Occurring Inhibitors. Acta Univ. Wratislaviensis 868, 33-40.

11 – Bode, W., Greyling, J., Huber, R., Otlewski, J. & Wilusz, T. (1989). The Refined 2.0 Å X-Ray Structure of the Complex Formed between Bovine β-Trypsin and CMTI I a Trypsin Inhibitor from Squash Seeds (Cucurbita maxima). Topological Similarity of the Squash Seeds Inhibitor with the Carboxypeptidase A Inhibitor from Potatoes. FEBS Letts. 242, 285-292. [PubMed]

10 – Hildebrandt, P. G., Copeland, R. A. Spiro, T. G., Otlewski, J., Laskowski, M. Jr. & Prendergast, R. G. (1988). Tyrosine Hydrogen-Bonding and Environmental Effects in Proteins Probed by Ultraviolet Resonance Raman Spectroscopy. Biochemistry 27, 5426-5433. [PubMed]

9 – Polanowski, A., Otlewski, J., Leluk, J., Wilimowska-Pelc, A. & Wilusz, T. (1988). A New Family of Serine Proteinase Inhibitors from Squash Seeds. Molecular and Cellular Regulation of Enzyme Activity. Biol. Zentralblatt 107, 45-49.

8 – Polanowski, A., Cieslar, E., Otlewski, J., Nienartowicz, B., Wilimowska-Pelc, A. & Wilusz, T. (1987). Protein Inhibitors of Trypsin from the Seeds of Cucurbitaceae Plants. Acta Biochim. Polon. 34, 395-406. [PubMed]

7 – Otlewski, J., Whatley, H., Polanowski, A. & Wilusz, T. (1987). Amino Acid Sequences of Trypsin Inhibitors from Watermelon (Citrullus vulgaris) and Red Bryony (Brionia dioica) Seeds. Biol. Chem. Hoppe-Seyler 368, 1505-1507.[PubMed]

6 – Otlewski, J. & Wilusz, T. (1985). The Serine Proteinase Inhibitors from Summer Squash (Cucurbita pepo). Some Structural Features, Stability and Proteolytic Degradation. Acta Biochim. Polon. 32, 285-293. [PubMed]

5 – Wieczorek, M., Otlewski, J., Cook, J., Parks, K., Leluk, J., Wilimowska-Pelc, A., Polanowski, A., Wilusz, T. & Laskowski, M. Jr. (1985). The Squash Family of Serine Proteinase Inhibitors. Amino Acid Sequences and Association Constants of Inhibitors from Squash, Summer Squash, Zucchini and Cucumber Seeds. Biochem. Biophys. Res. Commun. 126, 646-652. [PubMed]

4 – Otlewski, J., Polanowski, A., Leluk, J. & Wilusz, T. (1984). Trypsin Inhibitors in Summer Squash (Cucurbita pepo) Seeds. Isolation, Purification and Partial Characterization of the Inhibitors. Acta Biochim. Polon. 31, 267-278.[PubMed]

3 – Wilimowska-Pelc, A., Wieczorek, M., Otlewski, J., Leluk, J. & Wilusz, T. (1983). Immobilized Bowman-Birk Inhibitor for Selective Isolation of Chymotrypsin B from Bovine Pancreas. J. Chrom. 269, 22-27. [PubMed]

2 – Szewczuk, A., Kurowska, E., Prusak, E., Wilusz, T., Polanowski, A., Otlewski, J., Sobczyk, K. & Siemion, Z. (1983). Structural Differences between Trypsin Inhibitors Isolated from Cucurbitaceae Family Seeds: Immunological, CD and NMR Studies. Hoppe-Seyler’s Z. Physiol. Chem. 364, 941-947. [PubMed]

1 – Leluk, J., Otlewski, J., Wieczorek, M., Polanowski, A. & Wilusz, T. (1983) Preparations and Characteristics of Trypsin Inhibitors from the Seed of Squash (Cucurbita maxima) and Zucchini (Cucurbita pepo var. Giromontia). Acta Biochim. Polon. 30, 127-138.  [PubMed]