Projects

Ongoing projects:

Targeting cell surface proteoglycans with high affinity multimeric ligands and their cytotoxic conjugates – towards precision medicine for pancreatic cancer

Structure-function relationship in fibroblast growth factors signaling

Extracellular galectins as controllers of fibroblast growth factor receptor signaling

Dual warhead conjugates against FGFR-dependent cancers

Uncovering the funtions of FGF homologous factors – FHFs

Finished projects:

FGF1 analogue as a novel therapy for the treatment of diabetes mellitus

Highly stable mutants of human Fibroblast Growth Factor-1 (FGF1)

Spatial organization of FGF receptor 1 by multimeric ligand assemblies

Cytotoxic FGF-targeted peptibodies

In silico studies of Fibroblast Growth Factor

Antiapoptotc activity of human fibroblast growth factors 1 and 2

Highly cytotoxic FGF2-conjugates

Binding partners for FGF1 in nucleocytoplasmic translocation

Functional nanoparticles for medical applications

Aptamers

Repetitive scaffolds